Understanding Autism Spectrum Differential Diagnosis: An NDIS Guide for Families

Understanding Autism Spectrum Differential Diagnosis: An NDIS Guide for Families

• Gurprit Ganda
• Oct 29, 2025
• 8 min read

What Is Differential Diagnosis and Why Does It Matter for Autism?

When a child or adult shows signs that might be related to autism, professionals need to carefully work out exactly what is happening. This process is called differential diagnosis. Think of it like solving a puzzle where different pieces might look similar but fit into very different pictures.

Differential diagnosis means that doctors and psychologists carefully consider different possible explanations for the behaviours and challenges someone is experiencing. For autism spectrum disorder (ASD), this is especially important because many symptoms can overlap with other conditions.

The Bottom Line Up Front

If you are concerned about autism for yourself or a family member, understanding differential diagnosis helps you:

• Get the most accurate diagnosis possible

Get the most accurate diagnosis possible

• Access appropriate NDIS support faster

Access appropriate NDIS support faster

• Ensure your loved one receives treatments that truly help

Ensure your loved one receives treatments that truly help

• Avoid unnecessary interventions for conditions they don’t have

Avoid unnecessary interventions for conditions they don’t have

Understanding Autism Spectrum Disorder: What Are We Looking For?

The National Guideline for the assessment and diagnosis of autism in Australia provides clear and consistent recommendations for practitioners who conduct assessments, approved by the National Health and Medical Research Council (NHMRC).

Autism diagnosis requires persistent deficits in social communication and social interaction across multiple contexts, including deficits in social-emotional reciprocity, nonverbal communicative behaviors used for social interaction, and developing, maintaining and understanding relationships.

People with autism may also show:

• Repetitive movements or speech patterns

Repetitive movements or speech patterns

• Very focused or intense interests

Very focused or intense interests

• Need for sameness and routines

Need for sameness and routines

• Unusual responses to sensory experiences (sounds, lights, textures, tastes)

Unusual responses to sensory experiences (sounds, lights, textures, tastes)

Autism Comes in Different Levels

The DSM-5 categorizes Autism Spectrum Disorder into 3 levels based on the amount of support needed: Level 1 requires support, Level 2 requires substantial support, and Level 3 requires very substantial support.

These levels help determine what kind of assistance someone might need in daily life.

Conditions That Can Look Like Autism: The Differential Diagnosis Process

One of the most challenging aspects of autism diagnosis is that several other conditions share similar characteristics. Let’s explore the main conditions that professionals need to consider.

1. Attention Deficit Hyperactivity Disorder (ADHD)

ADHD and ASD have significant symptom overlap, with co-occurrence rates as high as 40 percent. Both conditions involve problems with self-regulation, though children with ADHD typically have more issues with planning while those with ASD have more difficulties with attention to detail.

Key Differences:

• ADHD focus

  : Difficulty sustaining attention, impulsive decisions, hyperactive behaviour

ADHD focus

: Difficulty sustaining attention, impulsive decisions, hyperactive behaviour

• Autism focus

  : Social communication differences, need for sameness, intense focused interests

Autism focus

: Social communication differences, need for sameness, intense focused interests

While DSM-IV did not allow both diagnoses together, DSM-5 lifted this restriction because many individuals with ASD present with additional ADHD symptoms that benefit from specific treatment.

2. Intellectual Disability

Intellectual disability and autism frequently co-occur; to make both diagnoses, social communication should be below that expected for general developmental level.

Someone might have:

• Intellectual disability alone

Intellectual disability alone

• Autism alone

Autism alone

• Both conditions together

Both conditions together

The key is to determine whether social and communication challenges are greater than would be expected based on someone’s overall developmental level.

3. Social Communication Disorder

This is a newer diagnostic category that describes difficulties with social use of language without the restricted interests and repetitive behaviours seen in autism.

Social (pragmatic) communication disorder is diagnosed when there are deficits in social communication but no restricted repetitive behaviors, interests, or activities are present.

4. Anxiety Disorders

Many children and adults with anxiety may avoid social situations, seem “different” around others, or develop specific routines to manage their worries. However, the type of social dysfunction in anxiety differs from autism—anxiety-related avoidance is fear-based, while autism involves fundamental differences in understanding social cues and communication.

5. Language Disorders

Pure language disorders affect how someone understands or uses language but don’t include the social interaction differences or restricted interests seen in autism.

6. Sensory Processing Disorder

Motor stereotypies (repetitive movements) are commonly observed in both autistic and non-autistic youth and can also appear in children with anxiety, OCD, ADHD, and tic disorders.

Some children have sensory sensitivities without autism. The difference lies in whether these sensory issues occur alongside the core autism features of social communication differences and restricted interests.

How Professionals Make an Accurate Autism Diagnosis in Australia

The National Guideline was developed through extensive consultation with more than 1,200 organisations and people across Australia, including autistic adults, family members, clinicians and policy makers.

The Assessment Process Includes:

• Developmental History

  : Understanding early development, current challenges, and family history

Developmental History

: Understanding early development, current challenges, and family history

• Behavioral Observations

  : Watching how someone interacts, communicates, and responds to different situations

Behavioral Observations

: Watching how someone interacts, communicates, and responds to different situations

• Standardized Assessments

  : Using validated tools designed specifically for autism assessment

Standardized Assessments

: Using validated tools designed specifically for autism assessment

• Medical Evaluation

  : Ruling out hearing problems, vision issues, or other medical conditions

Medical Evaluation

: Ruling out hearing problems, vision issues, or other medical conditions

• Cognitive Assessment

  : Understanding thinking skills and learning patterns

Cognitive Assessment

: Understanding thinking skills and learning patterns

• Consideration of Other Conditions

  : Carefully evaluating whether symptoms might be better explained by another condition

Consideration of Other Conditions

: Carefully evaluating whether symptoms might be better explained by another condition

Early diagnosis and intervention are associated with better outcomes for autistic individuals and their families.

What This Means for NDIS Eligibility

Understanding how your diagnosis relates to NDIS access is crucial for Australian families.

NDIS Access Criteria for Autism

Level 2 and Level 3 autism diagnoses are more likely to create automatic eligibility for NDIS, while Level 1 diagnoses require additional evidence showing how autism affects day-to-day functioning.

For NDIS eligibility, you need to show:

• The disability is permanent

The disability is permanent

• It significantly affects your ability to participate in everyday activities

It significantly affects your ability to participate in everyday activities

• You need supports that relate to your disability

You need supports that relate to your disability

Applicants with Level 1 autism diagnosis need to demonstrate reduced ability in functional areas including communication, social interaction, mobility, learning, self-management, and self-care.

Functional Capacity Assessment

The NDIA has worked with Autism CRC to develop functional assessment approaches that, combined with diagnosis, provide a more contemporary and evidence-based method for identifying support needs.

This means showing how autism affects:

• Communication

  : How you express needs and understand others

Communication

: How you express needs and understand others

• Social interaction

  : Connecting with family, friends, and community

Social interaction

: Connecting with family, friends, and community

• Learning

  : Acquiring new skills and information

Learning

: Acquiring new skills and information

• Self-care

  : Managing personal hygiene, eating, dressing

Self-care

: Managing personal hygiene, eating, dressing

• Self-management

  : Organizing tasks, managing emotions, making decisions

Self-management

: Organizing tasks, managing emotions, making decisions

• Mobility

  : Moving around your environment safely

Mobility

: Moving around your environment safely

Why Accurate Differential Diagnosis Matters for Your Family

Getting the right diagnosis isn’t just about labels—it’s about accessing the right support.

When Diagnosis Is Accurate:

For Individuals:

• Receive therapies that actually match their needs

Receive therapies that actually match their needs

• Access appropriate educational support

Access appropriate educational support

• Develop self-understanding and identity

Develop self-understanding and identity

• Connect with relevant peer communities

Connect with relevant peer communities

For Families:

• Access NDIS funding for suitable supports

Access NDIS funding for suitable supports

• Understand how to best support their loved one

Understand how to best support their loved one

• Connect with appropriate support networks

Connect with appropriate support networks

• Plan for the future with better information

Plan for the future with better information

For Service Providers:

• Deliver evidence-based interventions

Deliver evidence-based interventions

• Set appropriate goals

Set appropriate goals

• Measure progress effectively

Measure progress effectively

The Risks of Misdiagnosis

Diagnostic overshadowing can cause clinicians to overlook co-occurring disorders, attributing all symptoms to autism when other treatable conditions may be present.

This means someone might:

• Miss out on effective treatments for co-occurring conditions

Miss out on effective treatments for co-occurring conditions

• Receive interventions that don’t address their actual needs

Receive interventions that don’t address their actual needs

• Experience frustration when supports don’t help

Experience frustration when supports don’t help

• Face delays in accessing appropriate NDIS supports

Face delays in accessing appropriate NDIS supports

Accessing Autism Assessment in Bella Vista and Surrounding Areas

If you are concerned about autism for yourself or a family member, here’s how to move forward:

Step 1: Talk to Your GP

Your general practitioner can:

• Conduct initial screening

Conduct initial screening

• Provide referrals to specialists

Provide referrals to specialists

• Help coordinate your assessment team

Help coordinate your assessment team

Step 2: Gather Information

Collect information about:

• Developmental milestones

Developmental milestones

• Current challenges

Current challenges

• Strengths and interests

Strengths and interests

• Family history

Family history

• Reports from teachers or other professionals

Reports from teachers or other professionals

Step 3: Comprehensive Assessment

The national guideline drives better diagnostic standards so people receive optimum and comprehensive assessment that directs them to the right supports.

Seek assessment from qualified professionals including:

• Psychologists

Psychologists

• Paediatricians

Paediatricians

• Psychiatrists

Psychiatrists

• Speech pathologists

Speech pathologists

At Potentialz Psychology, our experienced team provides comprehensive autism assessments for adults following the National Guideline. We work with families throughout the Hills District, including Bella Vista, Norwest, Castle Hill, and Kellyville.

Step 4: Planning for NDIS Access

If autism is diagnosed, work with your assessing team to:

• Document functional impacts

Document functional impacts

• Gather evidence for NDIS application

Gather evidence for NDIS application

• Understand your support needs

Understand your support needs

• Connect with local NDIS providers

Connect with local NDIS providers

Evidence-Based Interventions for Autism Spectrum Disorder

Once diagnosis is confirmed, several effective interventions are available.

For Children and Adolescents:

Based on the Australian Psychological Society’s evidence-based interventions review:

Strong Evidence:

• Cognitive Behaviour Therapy (CBT)

  : Helps with anxiety and emotional regulation

Cognitive Behaviour Therapy (CBT)

: Helps with anxiety and emotional regulation

• Family-Based Interventions

  : Supports the whole family system

Family-Based Interventions

: Supports the whole family system

• Psychoeducation

  : Helps families understand and support autism

Psychoeducation

: Helps families understand and support autism

Emerging Evidence:

• Play therapy

Play therapy

• Parent-Child Interaction Therapy (PCIT) for younger children

Parent-Child Interaction Therapy (PCIT) for younger children

• Social skills training

Social skills training

For more information about therapeutic approaches for children, visit our

child psychologist services page

.

For Adults:

Many adults discover their autism diagnosis later in life. Support options include:

• Individual therapy for co-occurring anxiety or depression

Individual therapy for co-occurring anxiety or depression

• Social skills coaching

Social skills coaching

• Workplace accommodations

Workplace accommodations

• Peer support groups

Peer support groups

Supporting Co-Occurring Conditions

Most individuals diagnosed with ASD are also diagnosed with co-occurring conditions, with ADHD currently considered the most prevalent.

Common co-occurring conditions include:

• ADHD

  : See our guide on

  ADHD assessment and treatment

ADHD

: See our guide on

ADHD assessment and treatment

• Anxiety disorders

  : Learn about

  anxiety support

Anxiety disorders

: Learn about

anxiety support

• Depression

  : Especially in adolescents and adults

Depression

: Especially in adolescents and adults

• Sleep difficulties

  : Common across all ages

Sleep difficulties

: Common across all ages

• Eating challenges

  : Including sensory-related food aversions

Eating challenges

: Including sensory-related food aversions

Each co-occurring condition deserves its own assessment and treatment plan. This is where the differential diagnosis process becomes crucial—identifying which symptoms relate to autism and which require additional intervention.

Practical Tips for Families Navigating the Diagnostic Process

Do:

✓ Keep detailed records of your concerns and observations

✓ Ask questions throughout the assessment process

✓ Seek second opinions if something doesn’t feel right

✓ Connect with autism support groups

✓ Focus on your loved one’s strengths, not just challenges

✓ Be patient—comprehensive assessment takes time

Don’t:

✗ Rush to conclusions before full assessment

✗ Compare your child to others with autism (everyone is unique)

✗ Dismiss your concerns if others say “they seem fine”

✗ Expect instant answers—diagnosis is a careful process

✗ Forget to care for yourself during this journey

Moving Forward with Hope and Understanding

Receiving an autism diagnosis—or discovering that challenges are related to a different condition—provides clarity and direction. Whether you are supporting a child, adolescent, or adult, accurate diagnosis opens doors to:

• Targeted interventions that truly help

Targeted interventions that truly help

• Understanding from family, educators, and employers

Understanding from family, educators, and employers

• Connection with others who share similar experiences

Connection with others who share similar experiences

• Access to NDIS support when needed

Access to NDIS support when needed

• Self-acceptance and identity development

Self-acceptance and identity development

Remember that autism is not a deficit—it’s a different way of experiencing and interacting with the world. With proper services and supports, individuals with autism can thrive socially and economically.

Test Your Knowledge

Your Next Steps

If you are concerned about autism or other neurodevelopmental conditions, we are here to help. At Potentialz Psychology in Bella Vista, we provide:

• Comprehensive autism assessments following National Guidelines

Comprehensive autism assessments following National Guidelines

• ADHD evaluations

ADHD evaluations

• Cognitive assessments (IQ testing)

Cognitive assessments (IQ testing)

• Support with NDIS applications

Support with NDIS applications

• Evidence-based psychological therapies

Evidence-based psychological therapies

• Family support and psychoeducation

Family support and psychoeducation

Contact us today:

• Phone:

  0410 261 838

Phone:

0410 261 838

• Location:

  Conveniently located in Bella Vista, NSW

Location:

Conveniently located in Bella Vista, NSW

• NDIS Provider:

  Yes—we support NDIS participants that are self-managed or plan managed.

NDIS Provider:

Yes—we support NDIS participants that are self-managed or plan managed.

• Medicare Rebates:

  Available for eligible clients with Mental Health Care Plans

Medicare Rebates:

Available for eligible clients with Mental Health Care Plans

Visit our

NDIS psychologist page

to learn more about how we can support you through the diagnostic and treatment process.

References

• American Psychiatric Association. (2022).

  Diagnostic and Statistical Manual of Mental Disorders

  (5th ed., text rev.). American Psychiatric Association Publishing.

  https://doi.org/10.1176/appi.books.9780890425787

American Psychiatric Association. (2022).

Diagnostic and Statistical Manual of Mental Disorders

(5th ed., text rev.). American Psychiatric Association Publishing.

https://doi.org/10.1176/appi.books.9780890425787

• Australian Psychological Society. (2024).

  Evidence-based psychological interventions in the treatment of mental disorders: A literature review

  (5th ed.). Australian Psychological Society.

Australian Psychological Society. (2024).

Evidence-based psychological interventions in the treatment of mental disorders: A literature review

(5th ed.). Australian Psychological Society.

• Whitehouse, A. J. O., Evans, K., Eapen, V., & Wray, J. (2023).

  National Guideline for the assessment and diagnosis of Autism Spectrum Disorders in Australia

  (2nd ed.). Autism CRC.

  https://www.autismcrc.com.au/access/national-guideline

Whitehouse, A. J. O., Evans, K., Eapen, V., & Wray, J. (2023).

National Guideline for the assessment and diagnosis of Autism Spectrum Disorders in Australia

(2nd ed.). Autism CRC.

https://www.autismcrc.com.au/access/national-guideline

• Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder.

  The Lancet, 392

  (10146), 508-520.

  https://doi.org/10.1016/S0140-6736(18)31129-2

Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder.

The Lancet, 392

(10146), 508-520.

https://doi.org/10.1016/S0140-6736(18)31129-2

• National Institute for Health and Care Excellence. (2021).

  Autism spectrum disorder in adults: diagnosis and management

  (NICE guideline CG142).

  https://www.nice.org.uk/guidance/cg142

National Institute for Health and Care Excellence. (2021).

Autism spectrum disorder in adults: diagnosis and management

(NICE guideline CG142).

https://www.nice.org.uk/guidance/cg142

• Rosen, T. E., Mazefsky, C. A., Vasa, R. A., & Lerner, M. D. (2018). Co-occurring psychiatric conditions in autism spectrum disorder.

  International Review of Psychiatry, 30

  (1), 40-61.

  https://doi.org/10.1080/09540261.2018.1450229

Rosen, T. E., Mazefsky, C. A., Vasa, R. A., & Lerner, M. D. (2018). Co-occurring psychiatric conditions in autism spectrum disorder.

International Review of Psychiatry, 30

(1), 40-61.

https://doi.org/10.1080/09540261.2018.1450229

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Tags:

• Bella Vista psychology
• neurodevelopmental assessment
• DSM-5 autism criteria
• evidence-based autism intervention
• differential diagnosis
• National Guideline autism
• autism ADHD overlap
• NDIS eligibility
• Hills District autism support
• co-occurring conditions
• autism diagnosis
• autism levels
• ADHD and autism
• functional capacity assessment
• autism assessment
• family support autism
• child psychologist
• autism spectrum disorder
• Autism
• Neurodiversity
• Psychological Assessments